Flow Imaging Microscopy

Particle Analysis with Vision®

Obtain the highest-resolution images to analyze the shape, size, and count of subvisible particles and microorganisms with FlowCam.

Identify the contents of your sample with confidence.

Ebook cover thumbnail
Ebook
Advancing Subvisible Particle Analysis This ebook, produced in collaboration with AAPS, offers insights into the latest flow imaging microscopy applications for identifying subvisible particles, including relevant USP chapters.
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Plankton ID cards
Phytoplankton Identification Image Gallery This plankton identification gallery provides example FlowCam images from freshwater, estuarine, and marine algal groups, including potential toxin producers, cyanobacteria, taste and odor producers, and shellfish HABs.
View Gallery
Organoid rendering
Application Note
Quality Control of Organoid and Tumoroid 3D Cell Clusters with FlowCam Learn about the advantages of using FlowCam to asses iPSC culture optimization methods and a study performed in collaboration with Corning Life Sciences.
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Scientist looking at vial
Application Note
Visible Particle Analysis in Biologics using Flow Imaging Microscopy Learn how FlowCam can be used to detect visible and gray zone particles in protein therapy samples and gain insight into the types of particulates present.
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FlowCam instrument rendering on lab bench with data on monitor
Ebook
The Ultimate Guide to Flow Imaging Microscopy Flow Imaging Microscopy is a powerful tool for detecting, identifying, and quantifying subvisible particles for a variety of applications
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FlowCam

Particle Analysis Applications

Leading flow imaging analysis for oceanographic research, municipal water quality monitoring, biophysical analysis of API aggregates, cell and gene therapy, food and beverage analysis, materials characterization and many other areas of research.

Ensure the safety and efficacy of your biologic drug products

Flow Imaging Microscopy is a recommended orthogonal method to Light Obscuration for determining subvisible particulate content in parenteral drug formulations per USP <1788>.

Due to its exceptional image quality, FlowCam has become an indispensable tool in biotherapeutics research, formulation, and development for proteins, nano-drug delivery systems, and cell and gene therapy products.

 

Download the Ultimate Guide to Flow Imaging Microscopy

Learn more about how Flow Imaging Microscopy can characterize subvisible and submicron API aggregates and other particulates using morphology and artificial intelligence.

FlowCam inner components schematic

In flow imaging microscopy, particles move through a flow cell as images are captured in real-time by a high-speed camera and processed by image analysis software.

How it Works

Particle Count, Size, and Morphology with Flow Imaging Microscopy

FlowCam rapidly acquires digital images of particles to measure particle size and morphology. Up to 50,000 particles/minute may be imaged in real time and analyzed based on more than 40 morphological parameters. Optional artificial intelligence tools for biopharmaceutical applications allow automated particle identification.

Learn how FlowCam works

 

FlowCam 8000 Series Brochure
Brochure
FlowCam 8000 Series Brochure

Helpful Resources

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Webinar
Algae and Cyanobacteria Blooms - Track, Predict, and Identify We partnered with AquaRealTime and Phytoxigene to present an example framework for a proactive and integrated monitoring program that guides you through the process of monitoring and identifying harmful algal blooms (HABs).
Watch webinar
Drug vials on table
White Paper
USP Reference Standards for Subvisible Particulate Matter A detailed review of the guidelines in USP <788>, <787>, and <789> and the recommendations in USP <1787> and <1788>.
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Workers in protective gear assembling electronics in a factory
Application Note
Monitoring Cleanliness in Electronics Manufacturing with Dynamic Image Analysis  An imaging-based analytical approach to particle monitoring, identification, and control in environments with strict cleanliness protocols.
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Interested in learning more?

  1. Get in Touch

    Tell us about your application and particle characterization needs.

  2. Have a conversation

    We're happy to set up a call to discuss your application and answer your questions.

  3. Discuss next steps

    Expand your knowledge with a seminar, demonstration, sample analysis, or obtain a quote.

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