Resources
Explore FlowCam technical content, ebooks, case studies, webinars, and videos. For applications including biopharma, water quality monitoring, aquatic research, and materials characterization.
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Press
An Exclusive Spectroscopy Interview on Flow Imaging Microscopy: Part 1
An interview with Dr. Austin Daniels in collaboration with the American Association of Pharmaceutical Scientists (AAPS)

Press
An Exclusive Spectroscopy Interview on Flow Imaging Microscopy: Part 2
An interview with Dr. Austin Daniels in collaboration with the American Association of Pharmaceutical Scientists (AAPS)

Webinar
Optimizing Biotherapeutic Formulations: The Role of Flow Imaging Microscopy
April 30th, 3:00 PM CET | 2:00 PM BST | 9:00 AM EDT


Application Note
Quality Control of Organoid and Tumoroid 3D Cell Clusters with FlowCam
Learn about the advantages of using FlowCam to asses iPSC culture optimization methods and a study performed in collaboration with Corning Life Sciences.

Webinar
The Value of Plankton and Particle Imaging in Student-Led Research
Learn the importance of FlowCam to enhance student learning and research through examples from all academic levels.

Case Study
Incorporating Advanced Microscopy Technology into STEM Education
A Case Study from the University of San Diego

Application Note
Visible Particle Analysis in Biologics using Flow Imaging Microscopy
Learn how FlowCam can be used to detect visible and gray zone particles in protein therapy samples and gain insight into the types of particulates present.

Published Research
Influential FlowCam Studies for Biopharmaceuticals
A digest of influential FlowCam studies in biopharmaceutical research.

Ebook
Advancing Subvisible Particle Analysis
This ebook, produced in collaboration with AAPS, offers insights into the latest flow imaging microscopy applications for identifying subvisible particles, including relevant USP chapters.

White Paper
Monitoring Subvisible Particles in Biotherapeutics
Flow Imaging Microscopy for Particle Quantification and Characterization
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Webinar
Algae and Cyanobacteria Blooms - Track, Predict, and Identify
We partnered with AquaRealTime and Phytoxigene to present an example framework for a proactive and integrated monitoring program that guides you through the process of monitoring and identifying harmful algal blooms (HABs).

Webinar
Using Flow Imaging Microscopy to Meet Particulate Matter Standards for Biotherapeutics
This webinar discusses how FIM instruments can help researchers align with USP guidance for monitoring subvisible particles and how this technique can be used to characterize visible particles to support visual inspection processes.

Technical Note
Using Trigger Mode with FlowCam 8400 Instruments
Sample preparation guidance to help FlowCam 8400 and FlowCam Cyano users quickly find the appropriate dilution factor required to achieve a target Particles per Used Image (PPUI) value of 1.20 or below.

White Paper
USP Reference Standards for Subvisible Particulate Matter
A detailed review of the guidelines in USP <788>, <787>, and <789> and the recommendations in USP <1787> and <1788>.

Press
Phytoplankton Monitoring in Gulf of Maine as a Signal of Climate Change Impacts
UNH research tracks the role of microscopic algae in sustaining marine biodiversity and ecosystems. Photo shared by University of New Hampshire.

Technical Note
Using File Processing Mode for FlowCam Method Development
A step-by-step guide to making the most of VisualSpreadsheet's File Processing Mode.

Press
New Technology Helps Beat Back Harmful Algal Blooms
The Maryland Department of Natural Resources is identifying and controlling toxic algae several ways, from sophisticated imaging to sonic waves. Photo by AJ Metcalf/DNR.

Application Note
Monitoring Microplastics Using Flow Imaging Microscopy
This application note describes advantages and limitations of traditional techniques for microplastics analysis and presents case studies that introduce Flow Imaging Microscopy as a high-throughput approach.

Application Note
Monitoring Subvisible Particles in AAV Therapies with Flow Imaging Microscopy
This study shows how flow imaging microscopy can be used to monitor and minimize AAV aggregation and other subvisible particles found in gene therapies.

Webinar
Flow Imaging Microscopy for Monitoring Particles in Gene Therapies
This webinar introduces FIM and discusses how it can be used to monitor subvisible particles in gene therapy drug products, including a case study in which FIM was used to analyze AAV formulations during an accelerated stability study.

Webinar
Using FlowCam to Build Phytoplankton & HAB Community Composition Profiles Impacting Water Supplies
Speaker: Katherine McNaught, Passaic Valley Water Commission

Technical Note
Capture Settings for Biopharmaceutical Applications | Part 2: Optimizing Settings
How capture settings influence accurate FlowCam analysis and a strategy for optimizing settings for specific applications.

Poster
Characterizing Subvisible Particles in Protein, Cell and Gene Therapies Using Flow Imaging Microscopy and FlowCam
Download

Poster
Flow Imaging Microscopy for Monitoring Visible Particles
Download

Technical Note
Best Practices for Using FlowCam 8000 at Sea
Resources, suggestions, and best practices from scientists and technical experts to help you prepare your FlowCam for your next ocean research cruise and help you optimize your FlowCam time at sea.

Technical Note
Capture Settings for Biopharmaceutical Applications | Part 1: Recommended Settings
Recommended capture settings and size parameters for accurately analyzing a variety of common particle types present in biopharmaceutical formulations

Application Note
Monitoring Cleanliness in Electronics Manufacturing with Dynamic Image Analysis
An imaging-based analytical approach to particle monitoring, identification, and control in environments with strict cleanliness protocols.

Brochure
FlowCam 8000 Series Brochure
FlowCam 8000 Series applications, technology, and specifications

Brochure
FlowCam 8000 and FlowCam VS Comparison
Side-by-side specification comparisons between FlowCam 8000 and FlowCam VS and a comparison of image quality

Brochure
FlowCam University
Learning at your pace: virtual training courses for FlowCam 8000, FlowCam Cyano, FlowCam 5000, and VisualSpreadsheet

Brochure
ALH for FlowCam Brochure
Benefits and specifications for ALH for FlowCam automated liquid handling

Brochure
FlowCam Product Portfolio

Webinar
Flow Imaging Microscopy for Subvisible Particle Analysis in Biotherapeutics
This webinar introduces flow imaging microscopy, an analytical technique commonly used to characterize subvisible particle content in biotherapeutic samples.

Press
Salmon farm ‘FlowCam’ helping to monitor Clickimin Loch
A salmon farm company is offering its help to a local group concerned about the water quality at the Clickimin Loch in Lerwick.

Brochure
VisualSpreadsheet Satellite Version
Analyze your FlowCam data on up to 3 external computers

Technical Note
Meeting USP Standards for Subvisible Particulate Matter with FlowCam
Flow Imaging Method

Press
Flow Imaging Microscopy for Harmful Algal Bloom Monitoring
Feature article from Journal AWWA, April 2024 issue

Video
Bioscience Association of Maine Member Spotlight
Spotlight on Yokogawa Fluid Imaging Technologies

Application Note
Flow Imaging Microscopy for Environmental and Agricultural Applications
Microplastics characterization, fiber analysis, atmospheric pollution, stormwater runoff contamination, livestock health, crop and soil sciences

Webinar
An Overview of FlowCam for Aquatic Applications
The history and principles of FlowCam and case studies demonstrating how FlowCam is used for plankton research projects and algae monitoring programs

Technical Note
Meeting USP Standards for Subvisible Particulate Matter with FlowCam LO
Light Obscuration Method

Application Note
FlowCam for Shellfish Aquaculture and Research
A review of shellfish applications including: reproduction, larvae, microalgae cultivation, and predators

Technical Note
FlowCam 8000 Series Configuration Guide

Technical Note
How to Care for Your FlowCam 8000 Flow Cell

Ebook
The Ultimate Guide to Flow Imaging Microscopy for Biotherapeutics
Flow Imaging Microscopy for biotherapeutic characterization, including protein formulations, and cell & gene therapies

Ebook
The Ultimate Guide to Flow Imaging Microscopy for Aquatic Life Sciences
Flow Imaging Microscopy for the marine and freshwater applications including plankton research, aquaculture, water quality monitoring, and more

Ebook
The Ultimate Guide to Flow Imaging Microscopy
Flow Imaging Microscopy is a powerful tool for detecting, identifying, and quantifying subvisible particles for a variety of applications

Application Note
Flow Imaging Microscopy for Wastewater Treatment Applications

Case Study
Detecting Contaminants in Stormwater Runoff with Hydro International
Customer: Hydro International

Case Study
Monitoring for Taste & Odor Algae at Newport News Waterworks
How FlowCam is used by one drinking water utility

Case Study
Protein Sciences Corporation Chooses FlowCam for Quality Analysis
Customer: Protein Sciences Corporation

Application Note
FlowCam Biopharma Applications Brochure
An overview of FlowCam instruments and applications for biopharmaceuticals, including protein therapeutics and cell and gene therapy

Application Note
FlowCam Materials Applications Brochure
An overview of FlowCam instruments and applications for materials characterization, including food and beverage, crop science, advanced materials, and more

Application Note
FlowCam for Microencapsulation Process Analysis

Application Note
Printer Toner Quality Assurance with FlowCam

Case Study
FlowCam for Manufacturing and R&D Fluid Cleanliness Measurement
Customer: Hunting Energy Services

Case Study
Particle Characterization Helps Deliver Uniform Carbon Nanotube Products to Customers
Customer: Nanocomp

Case Study
FlowCam Assists Harmful Algae Mitigation in Salmon Aquaculture
Read a case study featuring Scottish Sea Farms

Technical Note
Using Example FlowCam Aquatic Image Libraries

Technical Note
Fiber Analysis with Flow Imaging Microscopy

Technical Note
Obtaining Accurate Concentration Data with FlowCam

Published Research
Recent Notable FlowCam Studies in Aquatic Research
A digest of recently published studies in the fields of phytoplankton and zooplankton research.

Published Research
Notable Studies Comparing FlowCam to Light Microscopy
A digest of influential FlowCam studies in comparing flow imaging microscopy to manual light microscopy.

Video
What is Flow Imaging Microscopy?
Learn how Flow Imaging Microscopy works and see FlowCam in action

Video
FlowCam Innovations for Biopharma
Learn about the variety of FlowCam solutions available for your biopharmaceutical application

Video
FlowCam for Aquatic Research and Water Quality Monitoring
Learn how FlowCam can improve your water quality monitoring and marine and freshwater research.

White Paper
Five Key Benefits of Automating Flow Imaging Microscopy
Introducing ALH for FlowCam automated liquid handling

White Paper
Measuring Subvisible Particles and Aggregates using FlowCam LO
FlowCam LO combines flow imaging microscopy and light obscuration in a single instrument

White Paper
Characterizing Protein Aggregation With Orthogonal and Complementary Analytical Techniques
A study showing how flow imaging microscopy and DLS can work together to provide a comprehensive picture of aggregation in your protein therapeutic

White Paper
Robust AI Methods for Protein Biotherapeutics
VisualAI software for sample-agnostic image analysis with FlowCam

Poster
An Integrated and High-Speed Aproach to Monitoring Algae and Cyanobacteria
In Lakes, Reservoirs, and Finished Drinking Water

Published Research
Notable FlowCam Studies on Cyanobacteria
A digest of influential FlowCam studies on cyanobacteria.

White Paper
Early Detection of Aggregation in Formulations
FlowCam Nano for submicron particle characterization in biotherapeutics

Technical Note
Recommended Lab Equipment for FlowCam Users
A list of recommended items to help anyone setting up a new lab or who wants to ensure that all necessary items are available at installation.

White Paper
Orthogonal and Complementary Techniques: Combining FIM with LO to Characterize Biotherapeutics
Learn why it's important to characterize biotherapeutics with orthogonal techniques

Published Research
FlowCam Macro Research Digest
FlowCam Macro publications demonstrate its value for zooplankton characterization in aquatic and environmental research

Technical Note
FlowCam Quantitative Metrics and Camera Settings
The effect of background intensity on particle image analysis

Application Note
Flow Imaging Microscopy for the Oil and Gas Industry

Technical Note
21 CFR Part 11: Frequently Asked Questions
Frequently Asked Questions about 21 CFR Part 11 Compliance in VisualSpreadsheet software.
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